That depends on how much boost/drive pressure you plan to run, what RPM you plan to run it up to and how much lift.
I'm runing something like 180ish lbs because that's what Comp Cam's told me to run when I gave them the specs for what I was doing. Haven't had a rocker, or lifter, problem yet.
Rather than try to figure it all out yourself I'd just give a cam manufacturer like Crane or Comp a call and tell them what you've got and what you're looking to do and they can tell you what you need.