It would work, yes, but with that style of fuel system, you would have alot of difficulty getting rid of any air trapped in the heads and lines from when you build the system, and isn't the point of a FASS system to eliminate air issues? You certainly do not want to force air through your injectors, it is not kind to the nozzles and pintles, as fuel cushions those two parts' actions.
The best way to run a fuel system is a flow thru, return style system, nearly identical to the way our stock system is setup, just with the main components like the fuel bowl, factory regulator, and factory pump replaced with higher flowing pieces.
I would suggest evaluationg what your end goals are for your truck, and build a system based on that. It can be something as simple as a basic E-fuel system to a full blown large single pump and complete system rebuild.
Dave