[Updated at 8:51 p.m. ET] A large tornado is on the ground in Cherokee County, Alabama, about to cross into western Georgia, the National Weather Service said. The city of Rome, Georgia, appears to be in the path of the tornado.
[Updated at 8:48 p.m. ET] At least 25 people in Alabama died Wednesday as a result of severe storms and tornadoes, the state's emergency management director, Art Faulkner, told CNN.
[Updated at 8:14 p.m. ET] The following video shows the twister that hit Tuscaloosa, Alabama, shortly after 5 p.m. CT:
Video - Breaking News Videos from CNN.com
[Updated at 6:55 p.m. ET] The Tuscaloosa (Alabama) Sheriff's Department is getting reports of major structural damage inside and outside the city limits after a major storm or tornado hit the area less than an hour ago, Sgt. Andy Norris said.
The department is getting reports of trees on homes, roofs collapsed at homes and businesses. Many people are calling 911, saying they are trapped, Norris said. The department has not immediately received any reports of deaths.
[Updated at 9:30 a.m. ET] Some 269,000 people were without power, most of them in the metro Birmingham area, as of about 8:20 a.m. (9:20 a.m. ET), said Michael Sznajderman, spokesman for Alabama Power, which covers the southern two-thirds of the state. "We're chipping away" at them, he said, but crews may have to pause as the second line of storms approaches.