You'll have to either make a doghouse to fit the motor or relocate the radiator to make a dt466 work. That's a long mofo! Someone did it already, don't remember the name, but the pulleys were at the radiator.
I can't think of a reason the injectors won't work aside from the turn ing aspect of it. If you can use b codes in a psd, why won't it work the othe way around. How much oil will the stock hpop in it make?
should be able to get it tuned up from International, at least for a start. I know our DT530 is rated at 275 and could be turned up by International to 300, trouble was it put the torque above the handling of the Alison trans so it never got turned up.
Looks like TS performance makes a chip for them. Start looking at tractor pulling I'm sure you could find a lot of go fast goodies there.
2005 F350 Crew Cab Long bed
6.0L / Auto 4x4
SCT X3 5" Magnaflow
4" RCD lift, a bunch of stereo gear and a computer